DMP-1 (Dentin matrix protein1) is a member of the integrin ligand N-linked glycoprotein family.It is mostly found in bone,tooth and hypertrophic cartilage. DMP-1 plays an important role in dentin and bone mineralization. DMP-1 has multiple serine,glutamic acid and aspartic acid residues,a GAG attachement site and RGD motif. DMP-1 is proteolytically proceesed into mulitple fragemtns in the extracellular matrix (ECM) of bone and dentin.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~60-130 kDa DMP- 1 of human, mouse, and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 21 of rat DMP-1
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的DMP1蛋白發生免疫反應.
保存建議
提供的DMP1抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該DMP1抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.