Breast tumor kinase，Brk （also known as PTK6），is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~57 kDa Brk of human， mouse， and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 508 of human Brk
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Brk蛋白發生免疫反應.
保存建議
提供的Brk抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Brk抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
