Matriptase or MT-SP1 is an epithelial-derived type II transmembrane serine protease that is highly expressd in human cancer-derived cell lines. Matriptase cleaves and activates protease activated receptor-2，pro-urokinase plasminogen activator and pro-hepatocyte growth factor. Matriptase is strongly inhibited by the hepatocyte growth factor activator inhibitor type 1 （HAI-1），which is a reactive site loop of Kunitz domain and also a transmembrane serine protease inhibitor.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~75 kDa doublets of Matriptase in samples from human， mouse and rat， origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 629 of rat Matriptase
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Matriptase蛋白發生免疫反應.
保存建議
提供的Matriptase抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Matriptase抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
