Neuropilin 1 is a type 1 membrane-bound coreceptor to a tyrosine kinase receptor for both Vascular Endothelial Growth Factor and Semaphorin family members. Neuropilin 1 is invovled in axon growth and guidance,cell survival,migration,and invasion.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~100-130 kDa band of Neuropilin 1 in samples from human, mouse and rat, origins. A lower band ~50-70 kDa can also be detected, presumably to be the cleavage fragment of Neuropilin-1. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 816 of mouse Neuropilin 1
來源宿主
兔
反應性
經檢測驗證,可與小鼠、大鼠種屬來源的Neuropilin-1蛋白發生免疫反應.
保存建議
提供的Neuropilin-1抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Neuropilin-1抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.