IRF3 is interferon regulatory factor 3,a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta,as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3,a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta,as well as other interferon-induced genes.
應用類型
Western blotting (1:200 – 1:500). However, the optimal concentrations should be determined individually.
免疫原
Synthetic peptide of human IRF3
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的IRF3 Polyclonal蛋白發生免疫反應.
保存建議
提供的IRF3 Polyclonal抗體產品為100 ul 無色溶液,其濃度為N/A,溶解于包含有30%甘油, 1% BSA和0.02%硫柳汞的PBS緩沖液中.請將該IRF3 Polyclonal抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.