Sox genes encode for transcriptional regulators that are involved in the early embryonic develpoment and in the determination of cell fate. Sox2 is also known as SRY （sex determining region Y）-box2，contain genes that encode for the HMG-box domain that is responsible for DNA binding activity. Mutation of Sox2 genes is link to optic nerve hypoplasia and anophthalmia，a severe form of eye deformity.
應用類型
Western blotting （0.5-1 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been tested. The antibody detects ~35kDa of Sox2 in samples from mouse origins.
免疫原
Synthetic peptide surrounding amino acid 301 of human Sox2
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、豬、牛、狗、綿羊種屬來源的Sox-2蛋白發生免疫反應.
保存建議
提供的Sox-2抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Sox-2抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
