OX40 is also known as CD134 is a member of the tumor necrosis factor receptor superfamily (TNFR). OX40 plays an important role in CD4+ and CD8+T-cells and B-cells response. Binding of OX40 to its ligand,OX40L provides co-stimulatory signal to effector T-cells without CD28 activation.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the 50 kDa full length as well as the 30 kDa and 20 kDa subunits of OX40 in Western blot analysis. Reacts with rat. Other species have not been determined.
免疫原
Synthetic peptide surrounding amino acid 255 of rat OX40
來源宿主
兔
反應性
經檢測驗證,可與大鼠種屬來源的OX40蛋白發生免疫反應.
保存建議
提供的OX40抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該OX40抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.