Dectin-1also known as beta-glucan receptor is a small type II transmembrane receptor containing lectin-like carbohydrate recognition domain. Dectin-1 plays a role in beta-glucan dependant,nonopsonic recognition of zymosan by primary macropahge. Dectin-1 is expressed on macrophages and neutrophils and on some dendritic cells subpopulation.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes 28 kDa of Dectin-1 from samples of human origins. A ~16 kDa monomeric form and a 43 kDa glycoprotein can also be detected. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 161of human Dectin-1
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的Dectin-1蛋白發生免疫反應.
保存建議
提供的Dectin-1抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Dectin-1抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.