Xenopus Dickkopf (Dkk) was initially discovered as a Wnt antagonist that plays an important role in head formation. By far,four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains which are separated by a 50-55 amino acid linker region.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects ~38 kDa of Dkk3 in samples from mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 240 of rat Dkk3
來源宿主
兔
反應性
經檢測驗證,可與小鼠、大鼠種屬來源的DKK3蛋白發生免疫反應.
保存建議
提供的DKK3抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該DKK3抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.