Xenopus Dickkopf （Dkk） was initially discovered as a Wnt antagonist that plays an important role in head formation. By far，four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains which are separated by a 50-55 amino acid linker region. Dkk4 is a secreted glycoprotein and has three immune-reactive sites at 15-17kDa，30-32kDa and at 40kDa.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects ~40 kDa of Dkk4 in samples from human， mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 179 of mouse Dkk4
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的DKK4蛋白發生免疫反應.
保存建議
提供的DKK4抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該DKK4抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
