NFkB was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is activated by a wide variety of stimuli such as lipopolysaccharide （LPS），pro-inflammatory cytokines，and viral infection. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes the 105 kDa NFkB p105 in samples from human， mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 955 of human NFkB105
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的NFkB p105蛋白發生免疫反應.
保存建議
提供的NFkB p105抗體產品為200 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該NFkB p105抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
