Dipeptidyl peptidase 10 or DPP10 is a single-pass type II membrane protein that belongs to the S9B family of DPP serine proteases. The conserved serine residue which normally found in the serine proteases family is not present in DPP10. Thus,DPP10 has no detectable proteases activity as the active serine site is replaced by a glycine residue. DPP10 cleaves the terminal dipeptides from cytokines and chemokines and also facilitates the voltage-gated potassium channels. It is expressed mostly in the brain and is a potential target for asthma treatment.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~90-97 kDa DPP10 in samples from human, mouse and rat origins.
免疫原
Synthetic peptide surrounding amino acid 642 of mouse DPP10
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的DPP10蛋白發生免疫反應.
保存建議
提供的DPP10抗體產品為200 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該DPP10抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.