Comparative Gene Identification-58 (CGI-58) is a causal gene of Dorfman-Chanarin syndrome,a neutral lipid storage disease characterized by the presence of intracellular lipid droplets in tissues. CGI-58 comes from a large family of proteins characterized by an /B hydrolase fold that activates adipose triglyceride lipase thus,may involve in lipid metabolism.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~45 kDa of CGI-58 in 3T3 cell lysate. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 218 of human CGI-58
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的CGI-58蛋白發生免疫反應.
保存建議
提供的CGI-58抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該CGI-58抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.