Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. The family contains NCAM (for neuronal cell adhesion molecule),ICAM (for intercellular adhesion molecule),VCAM (vascular cell adhesion molecule),PECAM-1 (platelet/endothelial cell adhesion molecule-1),etc. ICAM-2 is involved in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion.
應用類型
Western blotting (0.5-4 ug/ml). It detects multiple isoforms of ICAM-2. However, the optimal concentrations should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 257 of mouse ICAM-2
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的ICAM-2蛋白發生免疫反應.
保存建議
提供的ICAM-2抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該ICAM-2抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.