PINK1 （PTEN-induced putative kinase 1） is a serine/threonine protein kinase found in mitochondria. PINK1 protects cell from .stress-induced mitochondrial dysfunction. Mutation in this gene is associated with the early onset of Parkinson’s disease.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes 55 kDa and 63 kDa isoforms of PINK1 in samples from human， nouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 488 of mouse PINK1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的PINK1蛋白發生免疫反應.
保存建議
提供的PINK1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該PINK1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
