The Toll-like receptor （TLR） family of proteins are characterized by a highly conserved Toll homology （TH） domain，which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is homologous to TLRs 1 and 6 and is highly expressed in the lymphoid tissues.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~75 kDa and 94 kDa isoforms of TLR10 in Jurkat cell lysate. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 513 of human TLR10
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、牛種屬來源的TLR10蛋白發生免疫反應.
保存建議
提供的TLR10抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該TLR10抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
