ALK7 or ACVR1C is a type I receptor for TGFB superfamily of signaling protein. Upon ligand binding,type I receptors phosphorylate cytoplasmic SMAD transcription factors,which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
應用類型
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate and rat kidney tissue lysate can be used as positive controls.
免疫原
Synthetic peptide surrounding amino acid 155 of mouse ALK-7
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的ALK-7蛋白發生免疫反應.
保存建議
提供的ALK-7抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該ALK-7抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.