LKB1 is a tumor suppressor that belongs to the serine/threonine kinase family. Mutation in LKB1 is link to Peutz Jeghers syndrome (PJS),a disorder characterized by the growth of polyps in the gastrointestinal tract. LKB1 regulate AMPK signaling pathway and may also play a role in chromatin remodeling,cell cycle arrest and cell polarity
應用類型
The antibody can be used for Western blotting (0.5–4 ug/ml).
免疫原
Synthetic peptide surroundign amino acid 294 of mouse LKB1
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的LKB1蛋白發生免疫反應
保存建議
提供的100 ug LKB1抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該LKB1抗體產品置于-20 °C冷凍保存,建議分裝使用以避免反復凍融.