AS160 is a 160 kDa Akt serine/threonine kinase substrate that plays a critical role in regulating insulin-stimulated exocytosis of glucose transporter GLUT4. Increased in insulin treatment stimulate phophorylation of AS160 that regulates GLUT4 translocation via inactivation of the Rab GTPase function.
應用類型
The antibody can be used for Western blotting (1–4 ug/ml).
免疫原
Synthetic peptide surrounding amino acid 186 of human AS160/TBC1.
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的AS160/TBC1蛋白發生免疫反應
保存建議
提供的100 ug AS160/TBC1抗體產品為無色溶液其濃度為0.5mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該AS160/TBC1抗體產品置于-20 °C冷凍保存,建議分裝使用以避免反復凍融.