Tuberous sclerosis complex （TSC） is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin （TOR），an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
應用類型
The antibody can be used for Western blotting （1–4 ug/ml）.
免疫原
Synthetic peptide surrounding amino acid 1075 of mouse TSC1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的TSC1蛋白發生免疫反應
保存建議
提供的200 ug TSC1抗體產品為無色溶液其濃度為0.5mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該TSC1抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
