TSC2 is important in regulating cell proliferation and tumor development. Mutations in either the TSC1 or TSC2 tumor suppressor genes caused tuberous sclerosis complex （TSC），an autosomal dominant tumor syndrome. Tuberin is a product of the TSC2 tumor suppressor gene. Tuberin form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin （TOR）.
應用類型
The antibody can be used for Western blot analysis （1-4 ug/ml）. However， the optimal conditions should be determined individually. Blocking peptide （Cat.# 3962BP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 1548 of rat TSC2
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的TSC2蛋白發生免疫反應
保存建議
提供的200 ug TSC2抗體產品為無色溶液其濃度為0.5mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該TSC2抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
