IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.
序列
重組鼠源干擾素-gamma蛋白產品，又稱Immune Interferon-γ, type II interferon, T cell interferon, MAF.其對應NCBI基因號為15978，對應Accession號為P01580.
來源宿主
提供的【IFN gamma】重組鼠源干擾素-gamma產品的來源為大腸桿菌重組表達.
溶解建議
重組鼠源干擾素-gamma產品請按照說明書建議進行溶解操作：Reconstitute in ddH?O to a concentration of 1 mg/ml. Further dilutions should be made into RPMI + 10% FCS and stored at 4°C for 1 week or –20°C for future use. .
