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中文名稱

【Serpin E1】重組人Serpin E1 / PAI-1(100 ug)

英文名字
Serpin E1/PAI-1, human recombinant
供應商
Biovision
產品貨號
4731-100
產品報價
¥已停產
產品說明書
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產品新聞
背景資料
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. They are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SERPINE1 and PLANH1, is a secreted protein which belongs to the serpin family. SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SERPINE1 defect in the plasma. High concentrations of SERPINE1 have been associated with thrombophilia which is an autosomal dominant disorder in which affected individuals are prone to develop serious spontaneous thrombosis.
序列
重組人Serpin E1/PAI-1蛋白產品,又稱Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1).其對應NCBI基因號為5054,對應Accession號為P05121.
來源宿主
提供的【Serpin E1】重組人Serpin E1/PAI-1產品的來源為人細胞重組表達.
溶解建議
重組人Serpin E1/PAI-1產品請按照說明書建議進行溶解操作:It is recommended to reconstitute the lyophilized Recombinant Human SERPIN E1 in PBS not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
保存建議
在您收到艾美捷發出的【Serpin E1】重組人Serpin E1/PAI-1產品后,建議將其置于-70°C保存.
其他
BioVision的公司總部在美麗的舊金山灣地區,它是全球生命科學公司的Leader,BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品,以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理,艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.
注意
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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