The C-terminal glycine carboxyl of Ubiquitin is synthetically modified to an aldehyde. Ubiquitin Aldehyde (Ub-H) is useful in the stabilization of ubiquitin-protein conjugates in vitro, enhancing their accumulation in cell lysates and tissue extracts. Inhibition of deubiquitinylating enzyme activity by Ub-H can be used to identify and confirm such activity and to determine the inhibition kinetics for a particular enzyme. Recommended concentration for maximal inhibition is 2-5 uM. Co-crystallization of ubiquitin aldehyde with specific deubiquitinylating enzymes (the inhibitor mimics the natural ubiquitin substrate) has also been used to probe enzyme:substrate interactions.
重組人泛素醛產品為液體即用型，其溶液組成為：An aqueous solution containing 0.15 M HCl
保存建議
在您收到艾美捷發出的【Ubiquitin Aldehyde】重組人泛素醛產品后，建議將其置于-80°C. Do not lyophilize. Do not neutralize until immediately prior to use. Avoid presence of amino containing compounds.保存.
