- 中文名稱
【PRMT1】重組小鼠蛋白精氨酸甲基轉移酶1(1 mg)
- 英文名字
- PRMT1, mouse recombinant (Active)
- 供應商
- Biovision
- 產品貨號
- 4868-1000
- 產品報價
- ¥已停產

- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868.
- 產品新聞

- 背景資料
- PRMT1 methylate’s (mono & asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-rich domain (may methylate HNRNPA1 and histones) methylate’s SUPT5H. The PRMT1 protein functions as a histone methyltransferase specific for H4. PRMT1 is an essential factor in oncogenesis and is a potential novel therapeutic target in cancer. PRMT1-mediated methylation serves as a positive modulator of IR/IRS-1/PI3K pathway and glucose uptake in skeletal muscle cells. CAF1 is a new regulator of PRMT1-dependent arginine methylation. PRMT1 arginine-methylate’s MRE11 therefore it regulates the activity of MRE11-RAD50-NBS1 complex during the intra-S-phase DNA damage checkpoint response. PRMT1 plays a post-translationally part in regulating the transcriptional activity. PRMT1 is found predominantly in the cytoplasm, though a fraction of PRMT1 is located in the nucleus.
PRMT1 Mouse Recombinant fused with His-MBP tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 750 amino acids and having a molecular mass of 84 kDa. The PRMT1 is purified by proprietary chromatographic techniques.
- 序列
- 重組小鼠蛋白精氨酸甲基轉移酶1蛋白產品,又稱Protein arginine N-methyltransferase 1, Histone-arginine N-methyltransferase PRMT1, Interferon receptor 1-bound protein 4, Histone-arginine N-methyltransferase PRMT1, Interferon receptor 1-bound protein 4.其對應NCBI基因號為15469,對應Accession號為Q9JIF0.
- 來源宿主
- 提供的【PRMT1】重組小鼠蛋白精氨酸甲基轉移酶1產品的來源為大腸桿菌重組表達.
- 溶解建議
- 重組小鼠蛋白精氨酸甲基轉移酶1產品為液體即用型,其溶液組成為:Liquid in 40mM Tris-HCl pH 8.0, 100mM NaCl, 4mM MgCl2, 2mM DTT & 40% glycerol.
- 保存建議
- 在您收到艾美捷發出的【PRMT1】重組小鼠蛋白精氨酸甲基轉移酶1產品后,建議將其置于-80°C保存.
- 其他
- BioVision的公司總部在美麗的舊金山灣地區,它是全球生命科學公司的Leader,BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品,以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理,艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.

- 注意
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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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