MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2 is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases and is considerably higher in severe fibrosis patients . MIA2 is induced by IL6, TGF-? and conditioned medium from activated hepatic stellate cells. MIA2 is is mainly expressed in hepatocytes. MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa. The MIA2 is purified by proprietary chromatographic techniques.
序列
重組人MIA-2蛋白產品,又稱Melanoma inhibitory activity protein 2, Melanoma inhibitory activity protein 2.其對應NCBI基因號為117153,對應Accession號為Q96PC5.
來源宿主
提供的【MIA 2】重組人MIA-2產品的來源為大腸桿菌重組表達.
溶解建議
重組人MIA-2產品請按照說明書建議進行溶解操作:Reconstitute in sterile H?O at >100 ug/ml. Reconstituted MIA2 should be stored in working aliquots at -20°C. .