Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the regulation of the feeding behavior. Intracerebroventicular injection of nesfatin-1 reduces body weight in rats be affecting the animal food intake.
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重組小鼠Nesfatin-1蛋白蛋白產品,又稱Nesfatin 1, Nucleobindin-2, DNA-binding protein NEFA, Prepronefastin.其對應NCBI基因號為654,NCBI基因別稱為BMP6;該基因種屬來源為人源,對應Accession號為P22004 .該蛋白產品又稱Nesfatin 1等.