- 中文名稱
【PEDF】再生人PEDF(100 ug)
- 英文名字
- PEDF, human recombinant
- 供應商
- Biovision
- 產品貨號
- 4988-100
- 產品報價
- ¥已停產

- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868.
- 產品新聞

- 背景資料
- PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50,000 dalton glycoprotein created and secreted in many tissues all the way through the body. A key component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. Additionally, PEDF is capable to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The recognition of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. The unique range of PEDF activities associate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF in addition has the potential to be functional in the treatment of various angiogenesis-related diseases including a number of cancers. Recombinant human PEDF produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 400 amino acids and having a molecular mass of 44.5 kDa.
- 序列
- 重組人PEDF蛋白產品,又稱Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35.其對應NCBI基因號為5176,對應Accession號為P36955.
- 來源宿主
- 提供的【PEDF】重組人PEDF產品的來源為大腸桿菌重組表達.
- 溶解建議
- 重組人PEDF產品請按照說明書建議進行溶解操作:The sterile filtered concentrated (1 mg/ml) protein solution was lyophilized with 20 mM phosphate buffer & 150 mM NaCl pH-7.4.
- 保存建議
- 在您收到艾美捷發出的【PEDF】重組人PEDF產品后,建議將其置于-20°C保存.
- 其他
- BioVision的公司總部在美麗的舊金山灣地區,它是全球生命科學公司的Leader,BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品,以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理,艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.

- 注意
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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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