Increasing evidence suggests a central role for the CD40L-CD40 signaling pathway in several immunogenic and inflammatory processes，including atherosclerosis. It was also found that CD40L-CD40 signaling pathways play an important role in several autoimmune diseases，including the X-linked hyper-IgM syndrome，collagen-induced arthritis，allergic encephalitis and multiple sclerosis，and acute and chronic graft vs. host diseases.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Recombinant murine CD40L （Cat.# 4015-10） can be used as a positive control.
免疫原
Recombinant murine CD40L
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的CD40L蛋白發生免疫反應.
保存建議
提供的CD40L抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該CD40L抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
