Fractalkine，also known as neurotactin，is a membrane-bound CX3C Chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids，a mucin stalk of 241 amino acids，a putative transmembrane domain of 18 amino acids，and an intracellular tail of 37 amino acids. Within the chemokine domain，the first two cysteine residues are separated by 3 amino acids （CX3C）. Fractalkine message is found in high abundance in the brain，kidney，lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells and may play a role in brain inflammation.
應用類型
Western blot analysis （0.5-4 ug/ml）. Per researcher’s feedback， it can also be used in immunoprecipitation （4-8 ug/ml）， and Immunohistochemistry （10-20 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
E. coli-expressed recombinant human Fractalkine
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Fractalkine蛋白發生免疫反應.
保存建議
提供的Fractalkine抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Fractalkine抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
