IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells，which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper （CD4+） cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally，IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages，NK cells，and neutrophils. Murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.
應用類型
Western blot analysis （0.5-1 ug/ml） and neutralization （0.2-1 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
E. coli expressed murine IFN-gamma
來源宿主
兔
反應性
經檢測驗證，可與小鼠種屬來源的IFN gamma蛋白發生免疫反應.
保存建議
提供的IFN gamma抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有50%甘油和0.02%硫柳汞的PBS （pH 7.2）緩沖液中.請將該IFN gamma抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
