IL-15 is a member of the four alpha-helical bundle family of cytokines with a molecular weight of 14-15 kDa. Its in vitro activity is very similar to IL-2,except that IL-15 utilizes the IL-15 receptor alpha subunit for binding. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes,natural killer cells,macrophages,and monocytes. It also activates a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses,allograpt rejection,and the pathogenesis of autoimmune diseases.
應用類型
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli-expressed mouse IL-15
來源宿主
兔
反應性
經檢測驗證,可與小鼠種屬來源的IL-15蛋白發生免疫反應.
保存建議
提供的IL-15抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)緩沖液中.請將該IL-15抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.