IP-10 (interferon-gamma induced protein 10 kDa; in mouse also called cytokine responsive gene 2,Crg-2,or mob-1) is a highly inducible,primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. Like Mig,IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes,natural killer and T-cell migration,regulation of T-cell and bone marrow progenitor maturation,modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor,CXCR3.
應用類型
Western blot analysis (0.5-2 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli-expressed recombinant rat IP-10
來源宿主
兔
反應性
經檢測驗證,可與大鼠種屬來源的IP-10蛋白發生免疫反應.
保存建議
提供的IP-10抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)緩沖液中.請將該IP-10抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.