RANTES （regulated upon activation，normal T-cell expressed and secreted） is a 70-amino acid CC chemokine originally cloned from T-cell-specific sequences-enriched cDNA libraries. Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T-cells and eosinophils，as well as an activator of basophils for histamine release. In contrast to other CC chemokines，RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases.
應用類型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. RAW264.7 cells treated with LPS （15 hr） can be used as a positive control.
免疫原
E. coli-expressed mature rat RANTES （a.a. 1-70）
來源宿主
兔
反應性
經檢測驗證，可與小鼠、大鼠種屬來源的RANTES蛋白發生免疫反應.
保存建議
提供的RANTES抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）緩沖液中.請將該RANTES抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
