Leptin is a recently identified protein product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin have been found to be obese and diabetic and to have reduced activity，metabolism and body temperature. cDNA clones encoding leptin have been isolated from human，simian，mouse and rat cells. The expression of leptin mRNA has been shown to be restricted to adipose tissue. Leptin plays an important role in reproduction，immunological response and neuroendocrine signaling.
應用類型
Western blot analysis （0.5-2 ug/ml）. However， the optimal conditions should be determined individually. Recombinant rat Leptin （Cat.# 4368-02） can be used as a positive control. Other applications have not been tested.
免疫原
E. coli-expressed recombinant rat Leptin
來源宿主
兔
反應性
經檢測驗證，可與小鼠種屬來源的Leptin蛋白發生免疫反應.
保存建議
提供的Leptin抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Leptin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
