TGF-B (transforming growth factor-beta) is a family of multifunctional proteins. TGF-B was originally identified for its ability to induce the growth of normal rodent fibroblast in soft agar. It is now known that TGF-B is a potent growth inhibitor of many normal and transformed cell lines. It regulates normal cell growth,development and tissue remodeling following injury. TGF-B is produced as latent high molecular weight complexes. The activation of latent TGF-B is an important step in the regulation of its action.
應用類型
Western blot analysis (0.5-4 ug/ml) and Immunohistochemistry (10-20 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Recombinant TGF-B1
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠、豬種屬來源的TGF-beta1蛋白發生免疫反應.
保存建議
提供的TGF-beta1抗體產品為100 ug 無色溶液,其濃度為0.2 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)緩沖液中.請將該TGF-beta1抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.