BMPs （bone morphogenetic proteins） belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name，BMPs initiate，promote and regulate bone development，growth，remodeling and repair. In addition to its osteogenic activity，BMP-2 plays an important role in cardiac morphogenesis. It is also expressed in a variety of tissues such as lung，spleen，brain，liver，prostate ovary and small intestine.
應用類型
Western blotting （0.5-2 ug/ml）. It detects the 14 kDa monomer， 28 kDa dimer， as well as the 58 kDa tetramer of human BMP-2. Recombinant human BMP-2 （Cat.# 4577-10） can be used as a positive control. Reactivity to other species has not been tested.
免疫原
Recombinant human BMP-2
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的BMP-2蛋白發生免疫反應.
保存建議
提供的BMP-2抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該BMP-2抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
