BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name,BMPs initiate,promote and regulate bone development,growth,remodeling and repair. In vivo studies have shown that BMP-3 can independently induce cartilage formation.
應用類型
Western blotting (0.5-1 ug/ml) and Immunohistochemistry (20-30 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Recombinant human BMP-3
來源宿主
山羊
反應性
經檢測驗證,可與人種屬來源的BMP-3蛋白發生免疫反應.
保存建議
提供的BMP-3抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)緩沖液中.請將該BMP-3抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.