Lectins are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes,including embryogenesis,inflammatory responses,cell progression and metastasis. Galectin-3 can function intracellularly in controlling cell cycle and preventing T-cell apoptosis,and also extracellularly,in activating various cells,including monocytes/macrophages,mast cells,neutrophils,and lymphocytes. Human Galectin-3 is a globular 26.0 kDa protein containing 250 amino acid residues.
應用類型
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli expressed human Galetin-3
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的Galectin-3蛋白發生免疫反應.
保存建議
提供的Galectin-3抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Galectin-3抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.