ApoA1 is a 29.0 kDa protein produced in the liver and intestine，and secreted as the predominant constituent of nascent high-density lipoprotein （HDL） particle. ApoA1 which is found exclusively in HDL has a unique ability to capture and solubilize free cholesterol. This ApoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process，called reverse cholesterol transport，is thought to inhibit atherogenesis. For this reason HDL is also known as the “good cholesterol.” The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes，using a recombinant form of a naturally occurring variant of ApoA-I （called ApoA1 Milano）. Rat ApoA1 s a 27.4 kDa protein of 235 amino acid residues.
應用類型
Western blot analysis （0.5-4 ug/ml）. Recombinant rat ApoA1 （Cat.#: 4695-100） can be use as a positive control. However， the optimal conditions should be determined individually. Other applications have not been determined.
免疫原
E. coli expressed recombinant rat ApoA1
來源宿主
兔
反應性
經檢測驗證，可與大鼠種屬來源的ApoA1蛋白發生免疫反應.
保存建議
提供的ApoA1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該ApoA1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
