Follistatin belongs to a group of structurally-diverse diffusible proteins that binds to TGF-beta ligands and inhibit their activity by hindering access to signaling receptors. This naturally occurring antagonist binds to Activin,BMP-2,-4,-6,-7,Myostatin,GDF-11,and TGF-beta1. Follistatin is expressed in the pituitary,ovaries,decidual cells of the endometrium,and in some other tissues. Human Follistatin is a 31.5 kDa protein containing 288 amino acids.
應用類型
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli expressed human Follistatin
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的Follistatin蛋白發生免疫反應.
保存建議
提供的Follistatin抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Follistatin抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.