Human IGF-BP1 is a cysteine-rich secreted protein expressed in liver，decidual，and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions，whereas nonphosphorylated IGF-BP1 is stimulatory.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Recombinant human IGFBP-1 （Cat.# 4717-25） can be used as a positive control. Other applications have not been determined.
免疫原
E. coli expressed human IGF-BP1 （Cat.# 4717-25）
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的IGF-BP1蛋白發生免疫反應.
保存建議
提供的IGF-BP1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該IGF-BP1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
