Insulin is important in stimulating the uptake of glucose from blood in the skeletal muscle and adipose tissue. It is secrered by pancreatic B cells through a glucose sensing pathway. Insulin also increases cell permeability to monosaccharides，amino acids and fatty acids. Insulin is first formed as a precursor molecule，preproinsulin which is then processed into proinsulin and finally to the mature insulin hormone. A mature form of insulin has an A chain and a B chain that are connnected by two dilsufide bonds. Defects in insulin are the cause of type-II diabetes mellitus.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually.
免疫原
E. coli expressed recombinant human Insulin
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的Insulin蛋白發生免疫反應.
保存建議
提供的Insulin抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Insulin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
