Mouse complement C5a is a 77-amino acid peptide generated during complement activation from the alpha-chain of complement C5. Mouse C5a shares 60% and 82% amino acid sequence identity to human and rat C5a，respectively. C5a binds to a signaling G-protein coupled receptor （GPCR） （C5aR/CD88），inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils，and induces release of histamine in basophils and mast cells.
應用類型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Recombinant mouse C5a （Cat.# 4895A-20） can be used as a positive control. Other applications have not been determined.
免疫原
E. coli expressed mouse C5a
來源宿主
兔
反應性
經檢測驗證，可與小鼠種屬來源的C5a蛋白發生免疫反應.
保存建議
提供的C5a抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該C5a抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
