【干冰】Anti-Cu/Zn SOD (RABBIT) Antibody - 600-401-F20-【干冰】Anti-Cu/Zn SOD (RABBIT) Antibody - 600-401-F20代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity.

免疫原: Cu/Zn SOD Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to human Cu/Zn SOD.

反應性: Anthozoa (Coral); Bovine (Bos Taurus); Canine (Dog); Cricetinae (Hamster); H. sapiens (Human); Invertebrate; Leporidae (Rabbit); Mollusk; Mus musculus (Mouse); Oryzias melastigma (Fish); Ovis aries (Sheep); Perna viridis (Mussel); Rattus (Rat); Simiiformes (Monkey); Sus scrofa domesticus (Pig, Porcine, Swine); Xenopus laevis (African clawed frog)

保存建議: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。