- 中文名稱
【干冰】Anti-TMEM59L (RABBIT) Antibody - 600-401-FJ9
- 英文名字
- 【干冰】Anti-TMEM59L (RABBIT) Antibody - 600-401-FJ9
- 供應商
- Rockland
- 產品貨號
- 600-401-FJ9
- 產品報價
- ¥詢價/100ug

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
- 應用類型
- ELISA,Immunohistochemistry,IF Microscopy,Western Blot,
- 免疫原
- Anti-TMEM59L antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near C-terminus of human TMEM59L.
- 來源宿主
- Rabbit
- 反應性
- H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
- 保存建議
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年,是一家老牌抗體原產企業,其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體,包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素(Ubiquitin)等識別抗體,應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外,Rockland也生產特別齊全的二抗,包括純化、生物素、HRP/ALP、熒光標記二抗,應用十分廣泛。

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