【干冰】Anti-Histone H3 [Trimethyl Lys9] (RABBIT) Antibody - 600-401-I71-【干冰】Anti-Histone H3 [Trimethyl Lys9] (RABBIT) Antibody

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背景資料: Transcriptional silencing of specific genes and repetitive elements is known to be regulated partially through methylation of histone H3 at lysine 9, a hallmark of constitutive heterochromatin. In placenta, OCT2 expression and its ultimate function as a cation transporter is linked with the abundance of H3K9me3; when this methylation of histone H3 occurs in excess, mRNA for OCT2 decreases. Centromeres also are distinctly affected by the H3K9me3 modification, in that it co-localizes with several centromeric proteins, and affects the DNA methylation, particularly at the periphery of centromeric DNA. Gene expression is silenced when there is coordination between the H3K9me3 and H3K4modifications. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research.

免疫原: Histone H3 [Trimethyl Lys9] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic trimethylated peptide surrounding Lysine 9 of human Histone H3.2.

保存建議: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。