Synapsins are abundant brain proteins essential for regulating neurotransmitter release. All synapsins contain a short N-terminal domain that is highly conserved and phosphorylated by PKA or CaM kinase I. Phosphorylation of synapsin N-terminal domain at Ser9 inhibits its binding to phospholipids and diassociates synapsins from synaptic vesicles.
應用類型
Western blot analysis （0.5-4 ug/ml）. It detects the 60-80 kDa synapsins. Jurkat cell lysates and rat kidney tissue lysate can be used as positive controls. Blocking peptide （Cat.# 6008BP-50） is available separately.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 12 of human synapsin
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Synapsin蛋白發生免疫反應.
保存建議
提供的Synapsin抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Synapsin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
