GRASP Antibody detects GRASP protein. PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity. Therefore, GRASP antibody is ideal for investigators involved in neuronal plasticity and remodelling and more generally in Neuroscience.
應用類型
Western Blot,
免疫原
Anti-GRASP Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.
來源宿主
Rabbit
反應性
Mus musculus (Mouse); Rattus (Rat)
保存建議
Store vial at -20° C prior to opening.? This product is stable at 4° C as an undiluted liquid.? For extended storage, aliquot contents and freeze at -20° C or below.? Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
