Cyclophilin D is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins and thus their formation. Cyclophilin D is also a mitochondrial matrix protein, which plays a decisive role in mitochondrial permeability transition. It can bind to the immunosuppressant cyclosporine A and its overexpression suppresses the apoptosis in cancer cells.
序列
重組人親環蛋白 D 蛋白產品,又稱Peptidylprolyl isomerase D, PPID, CYPD, CYP-40.其對應NCBI基因號為5481,對應Accession號為Q08752.
來源宿主
提供的【Cyclophilin D 】重組人親環蛋白 D 產品的來源為大腸桿菌重組表達.
溶解建議
重組人親環蛋白 D 產品為液體即用型,其溶液組成為:1 mg/ml solution in PBS (pH 7.4) containing 10% glycerol.
保存建議
在您收到艾美捷發出的【Cyclophilin D 】重組人親環蛋白 D 產品后,建議將其置于-80°C保存.